Practice Paper on One Word Substitution for CLAT

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QUESTIONS ON ONE WORD SUBSTITUTIONQuestion: Read the following passage and decide the suitable one word for the given meaningFor too long, humankind has taken for granted the antibiotics that have held dangerous germs at bay. It was only about 70 years ago that penicillin, the world’s first antibiotic, came into widespread use and revolutionised medicine.​​ Its discoverer, Alexander Fleming, who won the Nobel Prize for his work, presciently warned that disease-causing organisms would become resistant if the drug was improperly used.​​ And that is just what has transpired. Although more antibiotics were subsequently discovered, these drugs have been given with such profligacy that pathogens resistant to them have evolved and spread with alarming rapidity.​​ ‘Superbugs’ resistant to almost all antibiotics have become a problem, raising worries of a return to the bad old days if much greater care was not exercised when prescribing existing drugs and sufficient encouragement for finding new ones was lacking.​​ Now, with its first global report on antimicrobial resistance, the World Health Organization has added its voice to the chorus of concern. The report has documented how bacterial resistance to antibiotics, including those of last resort, is a major health issue confronting all regions of the world.​​ Without urgent, coordinated action, “the world is headed for a post-antibiotic era in which common infections and minor injuries, which have been treatable for decades, can once again kill,” Keiji Fukuda, the health agency’s Assistant Director-General for Health Security, has warned.​​ The report also calls for greater emphasis on preventing infections from occurring, such as with better hygiene and by improving access to sanitation and clean water.For India, preventing antibiotic resistance from spiralling has to be a matter of urgency. The healthcare burden placed by bacteria such as Escherichia coli and Klebsiella pneumoniae, which have become resistant to many antibiotics and cause difficult-to-treat infections, is already quite substantial.Bacteria that have acquired a ‘New Delhi metallo-beta-lactamase (NDM)’ gene are resistant to even last-resort carbapenem antibiotics, forcing doctors to turn to colistin, a drug that is more than 50 years old. Halting the indiscriminate use of antibiotics is vital.​​ The Union Government has taken an important first step in that direction by introducing a stringent rule that prohibits medical stores from selling 24 key antibiotics without a doctor’s prescription.​​ Much more needs to be done, including getting doctors to prescribe antibiotics only when essential. Hospitals must pay attention to proper infection control. In a country so large and populous, with widely differing levels of healthcare reach, curbing the rise of antibiotic resistance is not easy. But it must be done.To control something from causing problemStringentBayChorusEmphasisAns. b.Explanation: on checking the meaning by replacing these words the question fits best in place of word bay. It is used in​​ ‘For too long, humankind has taken for granted the antibiotics that have held dangerous germs at​​ bay’. It clearly indicates that antibiotics have kept germs controlled from causing loss to humankind.To have knowledge of events before they take place.CurbRapidResistancePrescient​​ Ans. dExplanation: on checking the meaning by replacing these words the question fits best in place of word​​ prescient. It is used in ‘Its discoverer, Alexander Fleming, who won the Nobel Prize for his work,​​ presciently​​ warned that disease-causing organisms would become resistant if the drug was improperly​​ used’.​​ This states that Alexander through his work already warned that improper usage of​​ drugs will make disease causing organisms resistant.To reveal a secretBayConfrontTranspireEmphasisAns. cExplanation : on checking the meaning by replacing these words the question fits best in place of word​​ transpire. It is used in ‘Alexander Fleming, who won the Nobel Prize for his work,​​ presciently​​ warned that disease-causing organisms would become resistant if the drug was improperly used. And that is just what has​​ transpired’. It depicts the meaning getting known.To use resources wastefullyProfligacyResistanceSpirallingPathogensAns. aExplanation : on checking the meaning by replacing these words the question fits best in place of word​​ profligacy. It is used in ‘Although more antibiotics were subsequently discovered, these drugs have been given with such​​ profligacy​​ that pathogens resistant to them have evolved and spread with alarming rapidity’.​​ The meaning implicates that drugs ​​ are used wastefully which are making pathogens resistant.To repeat the same thing at regular intervalColistinChorusConfrontCurbAns. bExplanation : on checking the meaning by replacing these words the question fits best in place of word​​ chorus. It is used in ‘Now, with its first global report on antimicrobial resistance, the World Health Organization has added its voice to the​​ chorus​​ of concern’. It indicates that the World Health Organization​​ is continuously showing concern on antimicrobial resistance.To face a problem or difficultyResistantSubstantialConfrontProhibitAns. cExplanation: on checking the meaning by replacing these words the question fits best in place of word​​ confront. It is used in ‘The report has documented how bacterial resistance to antibiotics, including those of last resort, is a major health issue​​ confronting​​ all regions of the world’.​​ This indicates that regions of the world are facing problem of major health.To give something special importanceEmphasisBayPrescientSubstantialAns. aExplanation : on checking the meaning by replacing these words the question fits best in place of word​​ emphasis. It is used in ‘The report also calls for greater​​ emphasis​​ on preventing infections from occurring, such as with better hygiene and by improving access to sanitation and clean water’. It shows that special importance is being given on preventing infectionsTo increase continuouslyStringentConfrontSpirallingChorusAns. cExplanation: on checking the meaning by replacing these words the question fits best in place of word​​ spiralling. It is used in ‘For India, preventing antibiotic resistance from​​ spiralling​​ has to be a matter of urgency’. It depicts that continuous increase of ​​ antibiotic resistance is a matter of urgency.To be strict on someone or somethingStringentConfrontCurbBayAns. aExplanation : on checking the meaning by replacing these words the question fits best in place of word confront. It is used in ‘The Union Government has taken an important first step in that direction by introducing a​​ stringent​​ rule that prohibits medical stores from selling 24 key antibiotics without a doctor’s prescription’.​​ This states Union government is taking steps to introduce strict rules to prohibit​​ medical stores from selling 24 key antibiotics without a doctor’s prescription.​​ To keep in checkConfrontCurbPrescientEmphasisAns. bExplanation : on checking the meaning by replacing these words the question fits best in place of word curb. It is used in ‘Hospitals must pay attention to proper infection control. In a country so large and populous, with widely differing levels of healthcare reach,​​ curbing​​ the rise of antibiotic resistance is not easy’.​​ This depicts that to keep a check on rise in antibiotic resistance is not easy in so large an populous country.(function( $ ) { //footnotes $('.defaultNote').children(":first").css('cursor', 'pointer'); $('.defaultNote').children(":first").click(function(){ var gotoID = '#' + $(this).parent().attr('id'); $('html, body').animate( { scrollTop: $('a[href="' + gotoID + '"]').offset().top - 60, }, 250, 'linear' ) }); }(jQuery)); var numFormat = ",."; (function( $ ) { "use strict"; //do some cleaning on load var sortCells = $('td[data-sorting], th[data-sorting]'); sortCells.each(function(){ var first = $(this).text().trim().charAt(0); if (first == '@'){ var oldHTML = $(this).html(); var newHTML = oldHTML.replace('@', ''); $(this).html(newHTML); } }); function sortingTable(node, pos, ordBy){ var rows = node.children('tbody').children('tr').get(); rows.sort(function(a, b) { var X = $(a).children('td').eq(pos).text().toUpperCase(); var Y = $(b).children('td').eq(pos).text().toUpperCase(); if (numFormat != '.,'){ //we are dealing with a different locale and we need to do some //transformation in numbers X = convert2number(X); Y = convert2number(Y); } else { X = X.replace(/,/g, '').replace(/ /g, ''); Y = Y.replace(/,/g, '').replace(/ /g, ''); } var currencies = ['$', '¥', '£', '€']; var arrayLength = currencies.length; var XX = X; var YY = Y; for (var i = 0; i < arrayLength; i++) { XX = XX.replace(currencies[i], ''); YY = YY.replace(currencies[i], ''); } if (!isNaN(XX) && !isNaN(YY)){ var floatXX = parseFloat(XX); var floatYY = parseFloat(YY); return -(floatYY-floatXX) * ordBy; } else if (!isNaN(XX) && isNaN(YY)){ return -1 * ordBy; } else if (isNaN(XX) && !isNaN(YY)){ return ordBy; } else { if(X < Y) { return -1 * ordBy; } if(X > Y) { return 1 * ordBy; } return 0; } }); $.each(rows, function(index, row) { node.children('tbody').append(row); }); } function removeTableCellDecoration() { $("td[data-sorting], th[data-sorting]").removeClass('sortDecorator'); } //unbind the click event just in case we are loading more than one document $("td[data-sorting], th[data-sorting]").off('click'); $("td[data-sorting], th[data-sorting]").click(function(){ removeTableCellDecoration(); $(this).addClass('sortDecorator'); //get desired ordering var ordering = $(this).attr('data-sortOrdering'); if (ordering == 'ASC'){ var ordBy = -1; $(this).attr('data-sortOrdering', 'DESC'); } else { var ordBy = 1; $(this).attr('data-sortOrdering', 'ASC'); } var cellPosition = $(this).prevAll().length; var table = $(this).parents('table:first'); sortingTable(table, cellPosition, ordBy); }); function convert2number(str) { str = str.trim(); if (str.match(/^\d+/)) { //we have to take special care when the thousand separators are '.' var result_0 = str.replace(/\./g, '_@_'); var result_1 = result_0.replace(window.numFormat[0], '.'); var result = result_1.replace(/_@_/g, ''); result .replace(/ /g, ''); return result; } else { return str; } } }(jQuery));